The Carnivore Code AMA (Ask Me Anything) from Ben Greenfield Episode!

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In this AMA episode I answer questions from Ben Greenfield about my book, The Carnivore Code. It’s a deep dive into much of the science of an animal-based way eating. Prepare to learn a ton!

Time Stamps:

8:03 Carnivore diet background, framework

18:25 Is there a magic ratio of fat to protein we should aim for? What is rabbit starvation?

25:53 A Review of Issues of Dietary Protein Intake in Humans
https://pdfs.semanticscholar.org/4f00/4c6ff9159de2753b060df2ea1aab936db9ec.pdf

33:01. Is the decline in height and health fully attributable to plant agriculture or could it be due to industrialization?

38:43 Why do present day hunter-gatherers have no access to wild game?

42:54 How do we know that our high stomach acidity was driven by the consumption of animals? 

45:09 The Evolution of Stomach Acidity and Its Relevance to the Human Microbiome https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134116

50:51 How do herbivores detoxify plant toxins?

56:34 Coevolution of poisonous plants and large herbivores on rangelands 

https://journals.uair.arizona.edu/index.php/jrm/article/view/6858/6468

1:02:09 What are the studies of isothiocyanates in humans?

1:04:39  Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892312/

1:07:03  Why molecular hormesis is bad news

1:14:42  Effect of increasing fruit and vegetable intake by dietary intervention on nutritional biomarkers and attitudes to dietary change: a randomised trial  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060837/ 

1:18:03 Green tea extract only affects markers of oxidative status postprandially: Lasting antioxidant effect of flavonoid-free diet   https://www.researchgate.net/publication/11310865_Green_tea_extract_only_affects_markers_of_oxidative_status_postprandially_Lasting_antioxidant_effect_of_flavonoid-free_diet

1:20:08 Uric acid and glutathione levels during short-term whole body cold exposure https://pubmed.ncbi.nlm.nih.gov/8063192/

1:21:14 Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans https://www.nature.com/articles/ncomms14337

1:22:58  Is there an acceptable dose of isoflavones? 

1:23:53  Goitrogenic and Estrogenic Activity of Soy Isoflavones https://www.jstor.org/stable/3455387?seq=1

1:25:32 Isoflavones: estrogenic activity, biological effect and bioavailability  https://www.researchgate.net/publication/233538635_Isoflavones_Estrogenic_activity_biological_effect_and_bioavailability

1:26:48 Low Dietary Soy Isoflavonoids Increase Hippocampal Spine Synapse Density in Ovariectomized Rats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330193/

1:29:56 Is resveratrol really something we should avoid?

1:31:09  David Sinclair’s work on Resveratrol https://www.ncbi.nlm.nih.gov/pmc/?term=sinclair%2C+david+resveratrol

1:32:02 Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4‐month randomised trial in middle‐aged men https://pubmed.ncbi.nlm.nih.gov/25939591/#:~:text=Conclusion%3A%20In%20this%20population%20of,PSA%2C%20testosterone%2C%20free%20testosterone%2C

1:33:03 Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease https://pubmed.ncbi.nlm.nih.gov/26784973/

1:33:53 Prooxidant activity of research all in the presence of copper ions: mutagenicity in plasmid DNA https://www.sciencedirect.com/science/article/abs/pii/S0378427405001190?via%3Dihub

1:35:17 Resveratrol levels and all cause mortality in older community-dwelling adults https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346286/

1:36:16  resveratrol improves vascular function and mitochondrial number but not in glucose metabolism in older adults  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861959/

1:37:29  What are event-related potentials and how are they measured?

1:37:29 Food processing and emotion regulation in vegetarians and omnivores: an event-related potential investigation  https://www.sciencedirect.com/science/article/abs/pii/S0195666319300595?via%3Dihub

1:40:54 What really drives insulin resistance?

1:48:37  Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164353/

1:51:02 dietary stearic acid regulates mitochondria in vivo in humans  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081440/

1:53:52  What would you change in your diet if you had cancer? 

1:56:03 Halted Progression of Soft Palate Cancer in a Patient Treated with the Paleolithic Ketogenic Diet Alone: A 20-months Follow-up http://pubs.sciepub.com/ajmcr/4/8/8/

1:57:29 Complete Cessation of Recurrent Cervical Intraepithelial Neoplasia (CIN) by the Paleolithic Ketogenic Diet: A Case Report

https://www.researchgate.net/publication/322291809_Complete_Cessation_of_Recurrent_Cervical_Intraepithelial_Neoplasia_CIN_by_the_Paleolithic_Ketogenic_Diet_A_Case_Report

1:58:47  Are there any studies looking at telomere length in plant vs animal food diets? 

2:00:10 Processed meat, but not unprocessed red meat, is inversely associated with leukocyte telomere length in the Strongheart family study  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037876/

2:00:41 Epigenetic clock analysis of diet, exercise, education, and lifestyle factors https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361673/

2:00:54  Effects of diet on telomere length: systematic review and meta-analysishttps://www.karger.com/?DOI=10.1159/000486586

2:02:00  Dietary intervention modifies DNA methylation age assessed by epigenetic clock  https://doi.org/10.1002/mnfr.201800092

2:04:21  Increased lean red meat intake does not elevate markers of oxidative stress and inflammation in humans https://academic.oup.com/jn/article-lookup/doi/10.1093/jn/137.2.363 

2:07:40 Would eating fruit without the seeds be a healthy choice? 

2:08:07  Why does CarnivoreMD prefer unrendered fat?

2:00:37  Is dietary saturated fat something to be concerned about?

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