How Linoleic Acid is making you fat and Stearic Acid might just be the remedy with Brad Marshall, aka “The Croissant Diet Guy”

Brad Marshall is the author of the Blog Fire In A Bottle and the creator of The Croissant Diet.  Mildly obsessed with food and its history, his work focuses on trying to place current ideas about diet, including keto and carnivore diets into the framework of traditional Dietary patterns.  

Brad has a genetics degree from Cornell, a certificate from The French Culinary Institute, has studied cancer at Memorial Sloan-Kettering Cancer center and worked as a programmer for the Berkeley Drosophila Genome Project.  He spent the last 15 years raising rotationally grazed pastured pork on his farm in upstate New York while running a butcher shop, local food restaurant and USDA inspected meat processing facility.

Brad is also the founder of Firebrand Meats, which is dedicated to producing pork and poultry products that are low in Linoleic acid, the n6 polyunsaturated fat (PUFA) whose intake has seen a dramatic worldwide increase in the last century.  

https://reddit.com/r/SaturatedFat

Time Stamps:

0:13:55 Podcast Begins

0:15:14 Emmy’s story https://fireinabottle.net/emmys-story/

0:15:16 Change your fat, change your life

0:20:55 Disastrous Trends In American Bacon    https://fireinabottle.net/polyunsaturated-fat-pufa-in-pork-and-chicken/

0:23:55 The problem with pork and chicken in the US

0:30:12 Brad’s fascinating background

0:36:19 The croissant diet

0:45:27 Stearic acid vs linoleic acid

0:47:32 Plateaus on a ketogenic diet

0:53:54 Linoleic acid is the likely culprit

0:55:25 The shortcomings of the ketogenic understanding  

0:58:58 The feasting mimicking diet

1:04:46 ROS is Satiation https://fireinabottle.net/ros-is-satiation/

1:08:18 How linoleic acid affects blood glucose and satiety

1:12:21 All about insulin receptors

1:16:22 Fatty acids and ROS formation

1:28:29 Metformin

1:36:38 Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress https://www.sciencedirect.com/science/article/pii/S1550413107002562#bib64

1:41:40 Antioxidants prevent health-promoting effects of physical exercise in humans https://www.pnas.org/content/106/21/8665#:~:text=Notably%2C%20by%20blocking%20exercise%2Ddependent,vitamin%20C%20and%20vitamin%20E.

1:41:53 Stop megadosing Vitamin C

1:46:34 Butter Causes a High Level of Available Energy 8 Hours After a Meal https://fireinabottle.net/butter-causes-a-high-level-of-available-energy-8-hours-after-a-meal/

1:58:28 A diet enriched in stearic acid protects against the progression of type 2 diabetes in leptin receptor deficient mice (db/db) https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1002&context=physiology_etds

1:59:56 Dietary Stearic Acid Leads to a Reduction of Visceral Adipose Tissue in Athymic Nude Mice https://www.researchgate.net/publication/265650090_Dietary_Stearic_Acid_Leads_to_a_Reduction_of_Visceral_Adipose_Tissue_in_Athymic_Nude_Mice

2:01:29 The Body Fat of Obese Adults is Highly Unsaturated https://fireinabottle.net/the-body-fat-of-obese-adults-is-highly-unsaturated/

2:05:31 Oxidized metabolites of linoleic acid as biomarkers of liver injury in nonalcoholic steatohepatitis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578804/

2:12:22 Stearoyl-CoA Desaturase-1 Is Associated with Insulin Resistance in Morbidly Obese Subjects https://link.springer.com/content/pdf/10.2119/molmed.2010.00078.pdf

2:17:14 The Pima paradox

2:19:48 Classification of Obesity with Respect to Morbidity https://journals.sagepub.com/doi/abs/10.3181/00379727-200-43417?journalCode=ebma

2:20:56 Brad’ radical karaoke tribute

2:21:52 Where to find Brad Marshall

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